Who makes Systane? Amazon sales, products and sellers
Updated November 2026 with September 2026 data
At a glance
- Size
- Large
- $6.5M est./mo
- Trend
- Growing
- +25%, last 2 vs prior 2 months
- Ratings
- Strong
- 4.7 ★ · 169,325 reviews
- Who sells it
- Mostly one seller
- Top seller has 97% of units
Systane estimated monthly revenue on Amazon
Our read on Systane
Systane ranks 1 of 108 brands in Eye Drops on Amazon, with an estimated 24% of the category's revenue. Estimated revenue in September 2026 was $6.5M on 357,000 units, up 62% from $4.0M in June 2026, the first of 4 months of data. The trend is growing, at +25% over the last 2 months. The brand has 41 products selling and an average rating of 4.7 across 169,325 reviews. Systane Ultra Lubricating Eye Drops leads at 68,000 units per month. Sales are concentrated: Amazon accounts for 97% of units, while 12 sellers are active in total. Taken together, the picture is a large brand that is growing and sells mostly through one seller.
Top Systane products on Amazon
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| Product | Rating | Est. units/mo | Amazon link |
|---|---|---|---|
| Systane Ultra Lubricating Eye Drops | 4.8 ★35,410 reviews | 68,000 | Check price on Amazon |
| Systane Ultra Lubricating Eye Drops, 0.14 oz | 4.6 ★12,087 reviews | 57,000 | Check price on Amazon |
| Systane Complete Preservative Free Dry Eye Drops | 4.6 ★18,376 reviews | 43,000 | Check price on Amazon |
| Systane Ultra Preservative Free Dry Eye Relief Drops | 4.6 ★3,881 reviews | 20,000 | Check price on Amazon |
| Systane PRO PF Lubricating Eye Drops for Dry Eyes | 4.6 ★3,454 reviews | 19,000 | Check price on Amazon |
| Systane Hydration Lubricating & Hydrating Eye Drops, 0.34 fl | 4.6 ★4,951 reviews | 18,000 | Check price on Amazon |
| Systane Ultra Preservative Free Lubricant Eye Drops for Dry Eye | 4.8 ★10,978 reviews | 18,000 | Check price on Amazon |
| Systane Gel Drops Lubricant Eye Gel | 4.7 ★11,608 reviews | 17,000 | Check price on Amazon |
| Systane Hydration Lubricating & Hydrating Eye Drops, 30 Vials | 4.8 ★6,509 reviews | 14,000 | Check price on Amazon |
| Systane Complete Lubricant Dry Eye Relief Drops | 4.7 ★20,462 reviews | 13,000 | Check price on Amazon |
Who sells Systane
- Amazon97%
- JenSerCo1%
- Natural 123 -- NO FED TX --<1%
- PrimePortal<1%
- Talon<1%
Share of estimated units sold in September 2026, by the seller holding the Buy Box.
Place in its category
#1 of 108
Rank 1 of 108 brands in Eye Drops by estimated revenue in September 2026, with 24% of the category.
Frequently asked questions
Who makes Systane?
Systane is the brand name on 41 products we tracked on Amazon in September 2026 mostly in Eye Drops (Health & Household). The largest seller of Systane products that month was Amazon, with 97% of estimated units. Amazon listings don't show the brand owner's legal name, so the brand's own website is the place to confirm its parent company.
How much does Systane sell on Amazon?
Systane sold an estimated $6.5M on Amazon in September 2026, about 357,000 units. That is +62% compared with June 2026. These are Ecominsights estimates, not figures reported by the brand.
What are Systane's best-selling products on Amazon?
By estimated units sold in September 2026: 1. Systane Ultra Lubricating Eye Drops (about 68,000 units); 2. Systane Ultra Lubricating Eye Drops, 0.14 oz (about 57,000 units); 3. Systane Complete Preservative Free Dry Eye Drops (about 43,000 units).